KYOTO INSTITUTE OF TECHNOLOGY Department of Applied Biology Professor Dr. Masamitsu Yamaguchi

  • Poster Display Booth: A-43
  • Exhibition: BIO tech 2017 Academic Forum
  • Country: Japan
  • Development and application of Drosophila model for human peripheral nerve intractable diseases
  • Drosophila models for progressive peripheral nerve intractable diseases have been developed. Common genes and signal transduction pathways identified by these models will be introduced.

  • Date: June 28 (Wed) 14:30 - 15:00
  • Venue: ACA-1
  • Products/Services

    • Development and application of...

      Drosophila models for progressive peripheral nerve intractable diseases have been developed. Common genes and signal transduction pathways identified ...

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    Exhibitors' Product/Technology Seminar

    • Development and application of Drosophila model for human peripheral nerve intractable diseases

      Drosophila models for progressive peripheral nerve intractable diseases have been developed. Common genes and signal transduction pathways identified by these models will be introduced.

      1. Seminar Title Development and application of Drosophila model for human peripheral nerve intractable diseases
      2. Seminar Explanation Drosophila models for progressive peripheral nerve intractable diseases have been developed. Common genes and signal transduction pathways identified by these models will be introduced.
      3. Date:
        Jun. 28 (Wed)
      4. 14:30
      5. 15:00
      6. Venue: ACA-1
      7. Academic Forum Flag Yes

    Research/publisher profile

    • 研究内容

      1. Outlines/Features of Research We have focused on the Charcot-Marie-Tooth (CMT)-causing gene FIG4 and developed the transgenic flies to knockdown Drosophila homologus of this gene. By using this CMT model flies, we have carried out extensive genetic screen to identify genes and signaling pathways. These genes and pathways could be a novel diagnosis marker and therapeutic target.
      2. Differences with Conventional/Competitive Technologies Using Drosophila model, you can cut down the cost for the rearch that will accerelate your research. In contrast to the experiments with mammmals, there is essentially no ethical restriction in experiments using Drosophila.
      3. Expected Applications Because it can perform genome-wide screen to identify disease-related genes by using sophisticated genetic methods, Drosophila is useful for searching for targets of drug development. Besides, because of less amount of drug needed, preparation of food without heating, and easy screen of thousand chemical compounds in a month, use of Drosophila also has big advantage to evaluate lead compounds.
      4. Information July 1st, 2015-present, Director, The Center for Advanced Insect Research (CAIR), Kyoto Institute of Technology April 1st, 2014-June 30th, 2015, Director General of the Institute for the Promotion of Education and Research, Kyoto Institute of Technology April 1st, 2014-present, Director of the Insect Biomedical Research Center, Kyoto Institute of Technology September 7th, 2012-present, Visiting Professor, University of Science, Vietnam National University-HCMC October 1st, 2011-present, Honorary Professor, Hanoi Medical University, April 1st, 2006-March 31st, 2007, Head of Department, Department of Applied Biology, Kyoto Institute of Technology July 1st, 2001-present, Department of Applied Biology, Kyoto Institute of Technology, Professor, Molecular Genetics. March 31st, 1994-June 30th, 2001, Aichi Cancer Center Research Institute, Section Head, Cell Biology. August 1st, 1985-March 31st, 1994, Aichi Cancer Center Research Institute, Senior Researcher, Cell Biology April 1st, 1983-July 31st, 1985, Harvard Medical School, Department of Biological Chemistry, Post Doctoral Fellow (Supervisor; Dr Mel DePamphilis)

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